International Journal of Institutional Pharmacy and Life Sciences
نویسنده
چکیده
Wide range of biological activity of isoxazole makes it an important anchor in the field of medicinal chemistry. Already marketed drugs like Valdecoxib as COX-2 inhibitor, Cloxacillin and Dicloxacillin as beta lactamase resistant antibiotics having isoxazole core has beenproven to be efficacious drugs in present respective disease scenario. Therefore synthesis and evaluation of isoxazole containing moiety with wider therapeutic consequences is a topic of interest for the medicinal chemist. This mini review enumerates the reported synthetic strategies to synthesize isoxazole and its major therapeutic fields exploited in the literature. Thereby it is expected that this review will be beneficial for the researchers working in the same.
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